using System;

using System.Text.RegularExpressions;

public class Program

{

    public static void Main()

    {

        var item = " john smith (ABCDEFG) <js@email.com>\n" + 

            "target1 = 3333, j\n" + 

            "target2 1111, ";

        var pattern = @"target1 = (?<target1>\w+).*\ntarget2\s+(?<target2>\w+)";

        var m = Regex.Match(item, pattern);

        if (m.Success)

        {

            Console.WriteLine("target1: {0}", m.Groups["target1"]);

            Console.WriteLine("target2: {0}", m.Groups["target2"]);

        }

    }

}