using System;

using System.Linq;

public class Program

{

    public static void Main()

    {

        string valueString = "sam, mike,   , ,john  , Tom and jerry  , ";

        string[] arr = valueString.Split(',')

            .Select(x => x.Trim())

            .Where(x => !string.IsNullOrWhiteSpace(x))

            .ToArray();

        foreach( string w in arr) 

        {

        Console.WriteLine(w);

        }

​

    }

}